v1.0.0 - Initial Release

pcst-ad v1.0.0

Initial release of the PCST pipeline for Alzheimer's disease module detection.

Features

• Cell-type specific differential co-expression with FAVA
• PCST module detection integrating GWAS and PPI data
• Cross-cell-type Jaccard similarity heatmap
• Network visualization with GWAS p-value coloring
• GSEA pathway enrichment

Requirements

• Snakemake 8+
• Google Cloud Platform (for batch execution)