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Package: sxreveal
Title: A toolkit for demultiplexing single nuclei RNA sequencing samples by sex
Version: 0.3.2
Authors@R:
person("Nickolas", "Chu", , "nclchu@ucdavis.edu", role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-9860-7788"))
Description: This package is intended to be used to identify the sample a cell originated from, where cells from a male and female organism were mixed before 10X single nuclei sequencing. Sex assignment of cells are based on probabilities from density estimation using a Gaussian finite mixture model. This package was developed to take a Seurat object post dimensional reduction clustering as input.
License: MIT + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.1.9000
Imports:
BiocManager,
BSgenome.Mmusculus.UCSC.mm10,
dplyr,
EnsDb.Mmusculus.v79,
GenomeInfoDb,
GenomicRanges,
ggplot2,
grDevices,
mclust,
Seurat,
Signac,
stats,
R.utils
URL: https://github.com/nickolas-chu/sxreveal
BugReports: https://github.com/nickolas-chu/sxreveal/issues